Chemical Engineering students of the GAMER Group successfully defended their thesis proposal in partial fulfillment of their Chemical Engineering Methods of Research last December 28, 2022.
Antibacterial research is a significant area of interest in the fight against infectious diseases. Extracts from various parts of the plant, especially its essential oil, are used for antibacterial activity. Essential oils, such as Manila Elemi (Canarium luzonicum) oil, are widely known for their antibacterial properties. However, they are unstable, especially when exposed to the environment, causing immediate degradation. Cyclodextrin complexation is a cost-effective, flexible, and scalable approach for protecting the bioactive components of essential oil from deterioration. Cyclodextrin offers entrapment of bioactive chemicals — its hydrophobic cavity and the hydrophilic surface can form an inclusion complex with essential oil. Hence, essential oils can be immobilized with cyclodextrin to improve their stability.
The research of Daviene Daniella Canales, Ralph Laurence Mina, Lance Phillip L. Mosca, and David Paul P. Vergara, Chemical Engineering students, aims to synthesize and characterize α-, β-, and γ-cyclodextrin MOFs with immobilized essential oil from Manila Elemi. Assessment of antibacterial activity through the time-kill profile, minimum inhibitory concentration, and zone of inhibition against selected gram-positive, gram-negative, and spore-forming bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, and Clostridium difficile will be done.
Meanwhile, the rapidly expanding agricultural and metal industries, inappropriate waste disposal, fertilizers, and pesticides all contribute to the discharge of heavy metals into our rivers, soils, and environment. These heavy metals are toxic when ingested from contaminated water sources. Arsenic can cause swollen skin, abdominal pain, nausea, and muscle cramps. Prolonged exposure to arsenic can lead to cancer in the liver, lungs, kidneys, prostate, and skin. On the other hand, lead has the potential to harm nearly every organ and system in the body. Hence, there is a need to remove these metals from wastewater before discharging them into the environment.
The research of Cris Paolo L. Andal, Ashley Jorge C. Boco, Kyle Joshua C. Pitagan, and Jhon Nicko Y. Tongo, Chemical Engineering students, aims to synthesize adsorbents from different formulations of MIL-101(Fe), chitosan, and γ-Cyclodextrin and determine their effectiveness on Arsenic (III) and Lead (II) removal in water using central composite design. The composite beads of the compounds will be characterized using SEM-EDX, FTIR, PXRD, DSC, TG-DTA, and BET. Furthermore, the optimum composite design of the compounds will be determined to maximize the adsorption of As (III) and Pb (II). finally, the fitting isotherm and kinetic model of CS/MIL-101(Fe)/ɣCD will be determined.
Both of these researches will be done from 2023-2024.